If a little something makes a difference to some circumstance, it influences it, ordinarily in a positive way. If some thing tends to make no difference to some circumstance, it isn't going to influence it. This sort of are Dithyrambic and Nomic poetry, as well as Tragedy and Comedy; https://thermalcyclingchambersman57801.myparisblog.com/36319634/everything-about-localized-thermal-test-systems