And lastly, clonidine improves neuraxial opioids and, in combination with fentanyl, interacts within an additive way, which could decrease the dose of each component by sixty% for postoperative analgesia. For people who get dizzy when standing: This problem is known as orthostatic hypotension. Clonidine can make this problem worse. https://listfav.com/story21466861/the-basic-principles-of-onolidine