Bad/In depth Metabolizers, CYP2D6 The formation of the active metabolite, M1, is mediated by CYP2D6, a polymorphic enzyme. Somewhere around seven% from the populace has lessened activity with the CYP2D6 isoenzyme of cytochrome P450 metabolizing enzyme process. These men and women are “very poor metabolizers” of debrisoquine, dextromethorphan and tricyclic https://jasperkyipy.amoblog.com/the-basic-principles-of-bensedin-10mg-tablets-galenika-57756309