Pentobarbital will lessen the extent or effect of midostaurin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Solid CYP3A4 inducers could decrease midostaurin concentrations causing decreased efficacy. pentobarbital will lower the extent or effect of bexarotene by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.... https://genghise180juc5.thekatyblog.com/profile